Search results for "Tissue ingrowth"

showing 2 items of 2 documents

Additive Manufacturing of Multi‐Scale Porous Soft Tissue Implants That Encourage Vascularization and Tissue Ingrowth

2021

Medical devices, such as silicone-based prostheses designed for soft tissue implantation, often induce a suboptimal foreign-body response which results in a hardened avascular fibrotic capsule around the device, often leading to patient discomfort or implant failure. Here, it is proposed that additive manufacturing techniques can be used to deposit durable coatings with multiscale porosity on soft tissue implant surfaces to promote optimal tissue integration. Specifically, the “liquid rope coil effect”, is exploited via direct ink writing, to create a controlled macro open-pore architecture, including over highly curved surfaces, while adapting atomizing spray deposition of a silicone ink t…

Materials scienceSwinesoft tissue implantsmedical grade siliconeSiliconesBiomedical EngineeringTissue integrationPharmaceutical Science02 engineering and technology010402 general chemistry01 natural sciencesBiomaterialsMedical grade siliconechemistry.chemical_compoundSiliconeSettore BIO/10 - BiochimicaMaterials TestingAnimalsHumansPorosityImplant failureSoft tissueProstheses and Implantsmedical device coatings021001 nanoscience & nanotechnology0104 chemical scienceschemistrydevice-tissue interactionImplant0210 nano-technologyadditive manufacturingPorosityTissue ingrowthBiomedical engineeringAdvanced Healthcare Materials
researchProduct

Prosthetic strap system for simplified ventral hernia repair. Its results in a porcine experimental model.

2010

Abstract: Introduction Aiming to achieve a simplified ventral hernia repair, a proprietary shaped mesh was experimentally tested in the porcine model. The mesh is structured with a large central body and radiating straps. The friction of the straps passing through the tissues are hypothesized to be adequate to maintain the mesh in place during tissue ingrowth, avoiding classic point fixation while ensuring a wide coverage of the abdomen. Methods The mesh, having 6 radial straps, was placed using a sublay preperitoneal technique in 4 pigs. All straps were passed laterally through the abdominal wall and exteriorized from the skin. The straps were trimmed at the level of the skin, allowing the…

medicine.medical_specialtyFrictionSwineProsthesis ImplantationFixation (surgical)Ventral hernia; Prostheses and implants; Incorporation;Surgical fixation devices; FrictionmedicineAnimalsHerniaIncorporationProstheses and implantWound HealingSurgical fixation deviceVentral hernia repairExperimental modelSurgical Fixation Devicebusiness.industryAnatomySurgical Meshmedicine.diseaseHernia VentralSurgerybody regionsSettore MED/18 - Chirurgia GeneraleSurgical meshVentral herniaVentral herniaModels AnimalFeasibility StudiesSurgerybusinessTissue ingrowth
researchProduct